Pharmacokinetic-Pharmacodynamic Modeling and Simulation pdf epub mobi txt 電子書下載 2024

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Bonate, Peter L.

Springer Verlag

2005-10

400

$ 111.87

HRD

9780387271972

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发表于2024-11-24

Pharmacokinetic-Pharmacodynamic Modeling and Simulation epub 下載 mobi 下載 pdf 下載 txt 電子書下載 2024

Pharmacokinetic-Pharmacodynamic Modeling and Simulation pdf epub mobi txt 電子書下載 2024

圖書描述

A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. The purpose of this book is to present through theory and example how to develop pharmacokinetic models, both at an individual and population level. In order to do so, however, one must first understand linear models and then build to nonlinear models followed by linear mixed effects models and then ultimately nonlinear mixed effects models. This book develops in that manner - each chapter builds upon previous chapters by first presenting the theory and then illustrating the theory using published data sets and actual data sets that were used in the development of new chemical entities collected by the author during his years in industry. A key feature of the book is the process of modeling. Most books and manuscripts often present the final model never showing how the model evolved. In this book all examples are presented in an evolutionary manner.

Pharmacokinetic-Pharmacodynamic Modeling and Simulation 下載 mobi epub pdf txt 電子書