The Cancer Degradome pdf epub mobi txt 电子书下载 2025

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出版者:

作者:Edwards, Dylan (EDT)/ Hoyer-hansen, Gunilla (EDT)/ Blasi, Francesco (EDT)/ Sloane, Bonnie F. (EDT)

出品人:

页数:984

译者:

出版时间:2008-10

价格:$ 292.67

装帧:

isbn号码:9780387690568

丛书系列:

图书标签:

癌症
蛋白质降解
肿瘤微环境
药物靶点
蛋白质组学
癌症治疗
信号通路
PROTAC
分子生物学
生物化学

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具体描述

This book will aim to cover recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; how their activity can be imaged both in vitro and in vivo; the links that have emerged between proteolysis and cell signalling; how the degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to targeting proteolysis for therapy.