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Molecular Biology is a rapidly advancing field with a constant flow of new information and cutting-edge developements that impact our lives. Lewin's GENES has long been the essential resource for providing the teaching community with the most modern presentation to this dynamic area of study. GENES XI continues this tradition by introducing the most current data from the field, covering gene structure, sequencing, organization, and expression. It has enlisted a wealth of subject-matter experts, from top institutions, to provide content updates and revisions in their individual areas of study. A reorganized chapter presentation provides a clear, more student-friendly introduction to course material than ever before. - Updated content throughout to keep pace with this fast-paced field. - Reorganized chapter presentation provides a clear, student-friendly introduction to course material. - Expanded coverage describing the connection between replication and the cell cycle is included, and presents eukaryotes as well as prokaryotes. - Available with new online Molecular Biology Animations. - Online access code for the companion website is included with every new book. The companion website offers numerous study aids and learning tools to help students get the most out of their course. - Instructor's supplements include: PowerPoint Image Bank, PowerPoint Lecture Slides, and Test Bank.

Jocelyn E. Krebs, PhD-Associate Professor, University of Alaska, Anchorage

Jocelyn E. Krebs has been a member of the Department of Biological Sciences at the University of Alaska Anchorage since 2000. She received her B.A. in Biological Sciences from Bard College in 1991 and her PhD in Molecular and Cell Biology from the University of California Berkeley in 1997. Her research focuses on the mechanisms by which DNA transactions such as transcription and repair are accomplished in the context of chromatin. Her teaching interests are in Molecular Biology (taught at the undergraduate, graduate, and first-year medical school levels), as well as the Molecular Biology of Cancer.

Part 1 Genes and Chromosomes
Chapter 1 Genes Are DNA
Chapter 2 Genes Encode RNAs and Polypeptides
Chapter 3 Methods in Molecular Biology and Genetic Engineering
Chapter 4 The Interrupted Gene
Chapter 5 The Content of the Genome
Chapter 6 Genome Sequences and Gene Number
Chapter 7 Clusters and Repeats
Chapter 8 Genome Evolution
Chapter 9 Chromosomes
Chapter 10 Chromatin
Part 2 DNA Replication and Recombination
Chapter 11 Replication Is Connected to the Cell Cycle
Chapter 12 The Replicon: Initiation of Replication
Chapter 13 DNA Replication
Chapter 14 Extrachromosomal Replicons
Chapter 15 Homologous and Site-Specific Recombination
Chapter 16 Repair Systems
Chapter 17 Transposable Elements and Retroviruses
Chapter 18 Somatic Recombination and Hypermutation in the Immune System
Part 3 Transcription and Posttranscriptional Mechanisms
Chapter 19 Prokaryotic Transcription
Chapter 20 Eukaryotic Transcription
Chapter 21 RNA Splicing and Processing
Chapter 22 mRNA Stability and Localization
Chapter 23 Catalytic RNA
Chapter 24 Translation
Chapter 25 Using the Genetic Code
Part 4 Gene Regulation
Chapter 26 The Operon
Chapter 27 Phage Strategies
Chapter 28 Eukaryotic Transcription Regulation
Chapter 29 Epigenic Effects Are Inherited
Chapter 30 Regulatory RNA
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