Organic Chemistry of Drug Degradation pdf epub mobi txt 電子書 下載 2024


Organic Chemistry of Drug Degradation

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Li, Min
2012-9
336
$ 279.10
9781849734219

圖書標籤: 降解  藥物  化學   


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发表于2024-12-24

Organic Chemistry of Drug Degradation epub 下載 mobi 下載 pdf 下載 txt 電子書 下載 2024

Organic Chemistry of Drug Degradation epub 下載 mobi 下載 pdf 下載 txt 電子書 下載 2024

Organic Chemistry of Drug Degradation pdf epub mobi txt 電子書 下載 2024



圖書描述

The vast majority of drugs are organic molecular entities. A clear understanding of the organic chemistry of drug degradation is essential to maintaining the stability, efficacy, and safety of a drug product throughout its shelf-life. During analytical method development, stability testing, and pharmaceutical manufacturing troubleshooting activities, one of the frequently occurring and usually challenging events would be the identification of drug degradants and understanding of drug degradation mechanisms and pathways. This book is written by a veteran of the pharmaceutical industry who has first-hand experience in drug design and development, drug degradation mechanism studies, analytical development, and manufacturing process troubleshooting and improvement. The author discusses various degradation pathways with an emphasis on the mechanisms of the underlying organic chemistry, which should aid greatly in the efforts of degradant identification, formulation development, analytical development, and manufacturing process improvement. Organic reactions that are significant in drug degradation will first be reviewed and then illustrated by examples of drug degradation reported in the literature. The author brings the book to a close with a final chapter dedicated to the strategy for rapid elucidation of drug degradants with regard to the current regulatory requirements and guidelines. One chapter that should be given special attention is Chapter 3, Oxidative Degradation. Oxidative degradation is one of the most common degradation pathways but perhaps the most complex one. This chapter employs more than sixty drug degradation case studies with in-depth discussion in regard to their unique degradation pathways. With the increasing regulatory requirements on the quality and safety of pharmaceutical products, in particular with regard to drug impurities and degradants, the book will be an invaluable resource for pharmaceutical and analytical scientists who engage in formulation development, analytical development, stability studies, degradant identification, and support of manufacturing process improvement. In addition, it will also be helpful to scientists engaged in drug discovery and development as well as in drug metabolism studies.

Organic Chemistry of Drug Degradation 下載 mobi epub pdf txt 電子書

著者簡介


圖書目錄


Organic Chemistry of Drug Degradation pdf epub mobi txt 電子書 下載
想要找書就要到 小哈圖書下載中心
立刻按 ctrl+D收藏本頁
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用戶評價

評分

藥物降解雜質定性、生成機理,扛鼎之作。以化學反應和機理為主綫,梳理瞭近30年來的諸多案例。集腋成裘,見微知著。博觀而能慎思。

評分

藥物降解雜質定性、生成機理,扛鼎之作。以化學反應和機理為主綫,梳理瞭近30年來的諸多案例。集腋成裘,見微知著。博觀而能慎思。

評分

藥物降解雜質定性、生成機理,扛鼎之作。以化學反應和機理為主綫,梳理瞭近30年來的諸多案例。集腋成裘,見微知著。博觀而能慎思。

評分

藥物降解雜質定性、生成機理,扛鼎之作。以化學反應和機理為主綫,梳理瞭近30年來的諸多案例。集腋成裘,見微知著。博觀而能慎思。

評分

藥物降解雜質定性、生成機理,扛鼎之作。以化學反應和機理為主綫,梳理瞭近30年來的諸多案例。集腋成裘,見微知著。博觀而能慎思。

讀後感

評分

OCDD erratum <Organic Chemistry of Drug Degradation> 勘误 记号说明 example: Page.10 Paragraph.3 Line.-5 第10页,第3段,倒数第5行 -------------------------------- P.80 L.1 10-methyl-Δ1(9)-octalone-2 --------------------------------------- pyrrolidine ...

評分

OCDD erratum <Organic Chemistry of Drug Degradation> 勘误 记号说明 example: Page.10 Paragraph.3 Line.-5 第10页,第3段,倒数第5行 -------------------------------- P.80 L.1 10-methyl-Δ1(9)-octalone-2 --------------------------------------- pyrrolidine ...

評分

OCDD erratum <Organic Chemistry of Drug Degradation> 勘误 记号说明 example: Page.10 Paragraph.3 Line.-5 第10页,第3段,倒数第5行 -------------------------------- P.80 L.1 10-methyl-Δ1(9)-octalone-2 --------------------------------------- pyrrolidine ...

評分

OCDD erratum <Organic Chemistry of Drug Degradation> 勘误 记号说明 example: Page.10 Paragraph.3 Line.-5 第10页,第3段,倒数第5行 -------------------------------- P.80 L.1 10-methyl-Δ1(9)-octalone-2 --------------------------------------- pyrrolidine ...

評分

OCDD erratum <Organic Chemistry of Drug Degradation> 勘误 记号说明 example: Page.10 Paragraph.3 Line.-5 第10页,第3段,倒数第5行 -------------------------------- P.80 L.1 10-methyl-Δ1(9)-octalone-2 --------------------------------------- pyrrolidine ...

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