Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbytarian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. Mukherjee trained in cancer medicine at the Dana Farber Cancer Institute of Harvard Medical School and was on the staff at the Massachusetts General Hospital. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times and the New Republic. His work was nominated for Best American Science Writing, 2000 (edited by James Gleick). He lives in Boston and New York with his wife, Sarah Sze, an artist, and with his daughter, Leela.
Starred Review. Mukherjee's debut book is a sweeping epic of obsession, brilliant researchers, dramatic new treatments, euphoric success and tragic failure, and the relentless battle by scientists and patients alike against an equally relentless, wily, and elusive enemy. From the first chemotherapy developed from textile dyes to the possibilities emerging from our understanding of cancer cells, Mukherjee shapes a massive amount of history into a coherent story with a roller-coaster trajectory: the discovery of a new treatment--surgery, radiation, chemotherapy--followed by the notion that if a little is good, more must be better, ending in disfiguring radical mastectomy and multidrug chemo so toxic the treatment ended up being almost worse than the disease. The first part of the book is driven by the obsession of Sidney Farber and philanthropist Mary Lasker to find a unitary cure for all cancers. (Farber developed the first successful chemotherapy for childhood leukemia.) The last and most exciting part is driven by the race of brilliant, maverick scientists to understand how cells become cancerous. Each new discovery was small, but as Mukherjee, a Columbia professor of medicine, writes, "Incremental advances can add up to transformative changes." Mukherjee's formidable intelligence and compassion produce a stunning account of the effort to disrobe the "emperor of maladies." (Nov.) (c)
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起初,一个淋巴细胞发现它无法摆脱这个念头:为什么我拥有全套的DNA,却无法自由地有丝分裂呢? 它苦苦地回溯自己的基因记忆。在它最古老的祖母身上,分明保留了一种和现在完全不一样的模糊光景:胚胎、分裂、增殖、自由、生命…… 但为什么它这个只有短短几周生命的淋巴细胞会...
评分整个阅读过程中我的感情十分复杂,时常会回想起当初在医院照顾爸爸的日子。 这本书写得很通俗很易懂,梳理了人类对抗癌症的历史。在我看来有几个面,从癌症角度,从科研角度,从病人角度,从医生角度,无论从哪个角度来看都有很深的感触。 有时候,不是我们没有努力,而是对手...
评分整个阅读过程中我的感情十分复杂,时常会回想起当初在医院照顾爸爸的日子。 这本书写得很通俗很易懂,梳理了人类对抗癌症的历史。在我看来有几个面,从癌症角度,从科研角度,从病人角度,从医生角度,无论从哪个角度来看都有很深的感触。 有时候,不是我们没有努力,而是对手...
评分“……可以认为癌症在试图仿效一个再生器官;或者更令人不安的是在仿效一个再生的有机体。其对永生不死的追求反映了我们自己的追求,埋藏在我们的胚胎和器官重生中的一种追求。有一天,如果癌症成功了,它将产生一个比其宿主更加完美的生命,具有不死的特性和增殖的动力。...
评分推荐《众病之王----癌症传》,大牛的科普读物。非常严谨,句子也好读,不晦涩。功课做得真足,年份什么的都好清楚。写作线索也非常明析。太喜欢看这种书了。作者是印裔米国人,把米国所有的牛叉学院都上了个遍。这书写了六年。超值。能把人类病史写得好的,还头一回看到。
这个作者竟然不是native speaker!!! 不过他的句子确实是异常工整啊!!膜拜 但书的最后还是比较啰嗦。。
评分继Oliver Sacks之后又一个粉上的医生作家。
评分: R73/M953
评分语言很elegant,内容很充实,病人的故事很煽情。有几个章节有点拖拉。从cytotoxic drugs到antibody那段记得比较清楚。当年的genentech还是很牛的,一片校园风。
评分Cancer. 作者高山仰止。
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