The Emperor of All Maladies

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Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbytarian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. Mukherjee trained in cancer medicine at the Dana Farber Cancer Institute of Harvard Medical School and was on the staff at the Massachusetts General Hospital. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times and the New Republic. His work was nominated for Best American Science Writing, 2000 (edited by James Gleick). He lives in Boston and New York with his wife, Sarah Sze, an artist, and with his daughter, Leela.

出版者:Scribner
作者:Siddhartha Mukherjee
出品人:
页数:592
译者:
出版时间:2010-11-16
价格:USD 30.00
装帧:Hardcover
isbn号码:9781439107959
丛书系列:
图书标签:
  • 科普 
  • 癌症 
  • 医学 
  • 普利策奖 
  • 科学 
  • 生命 
  • cancer 
  • science 
  •  
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Starred Review. Mukherjee's debut book is a sweeping epic of obsession, brilliant researchers, dramatic new treatments, euphoric success and tragic failure, and the relentless battle by scientists and patients alike against an equally relentless, wily, and elusive enemy. From the first chemotherapy developed from textile dyes to the possibilities emerging from our understanding of cancer cells, Mukherjee shapes a massive amount of history into a coherent story with a roller-coaster trajectory: the discovery of a new treatment--surgery, radiation, chemotherapy--followed by the notion that if a little is good, more must be better, ending in disfiguring radical mastectomy and multidrug chemo so toxic the treatment ended up being almost worse than the disease. The first part of the book is driven by the obsession of Sidney Farber and philanthropist Mary Lasker to find a unitary cure for all cancers. (Farber developed the first successful chemotherapy for childhood leukemia.) The last and most exciting part is driven by the race of brilliant, maverick scientists to understand how cells become cancerous. Each new discovery was small, but as Mukherjee, a Columbia professor of medicine, writes, "Incremental advances can add up to transformative changes." Mukherjee's formidable intelligence and compassion produce a stunning account of the effort to disrobe the "emperor of maladies." (Nov.) (c)

Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

具体描述

读后感

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癌症源于我们自身的一些负责调节细胞生长的基础基因的突变。而这种突变基因导致的癌细胞有时会展现出永不停止的分裂。在合适的环境下癌细胞可以一直分裂下去,没有衰老的痕迹,这透露出永生的意味。而这种带着永生意味的分裂却会摧毁我们的身体,带来无可避免的死亡。 这真是...  

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这是我迄今为止读过最好的科普书。 毫 无疑问,这是一本工程浩大的经典,一本详实严谨的科学著作,同时,它也是一本史诗般的传记。如果说写作的对象在一定程度上决定写作的结果,那这本书的主题 ——被作者称为万疾之王的癌症,在我看来,应该是长长的人类疾病名单中(其实不...  

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本书的题记上说,美国1/3的女性和1/2的男性会得癌症。这样算来,一对夫妻终生不得癌症的概率仅为1/3,如再考虑双方的父母,一个人在一生中都不接触癌症患者的概率不会超过1/27。中国的数据和美国或有差异,但癌症早已是仅次于心脑血管病的国人第二大死因。考虑到癌症患者的痛苦...  

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2013年快过去3个月了,看了一堆书,这是第一本好书。 首先,作者很会讲故事,运用了很多小说上的技术,使人如看侦探小说。 其次,翻译流畅,李虎老师的翻译很流畅,没有磕磕盼盼的地方。 最后,这本书的装帧很喜欢。  

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很早就看完了,一直想要找个时间写这本书的书评,由于准备考研一直就把这个给拖后了。或许很多细节记得不是那么清楚了,我只想写写我看这本书的整个过程。 爸是在今年3月份查出癌症的,之前一直医生误以为是由于肾结石引起的左肾肿大变形,直到最后把左肾切除后做了活检才发现...  

用户评价

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cancer as metaphor. 把目标定为延长生命而非终结死亡

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这是一本癌症的传记,这个困扰了人类几千年的疾病。作者是个医生,专业知识扎实,文字又好,功课也做得足。虽然书并不短,但是用四百多页深入浅出的把癌症几千年的历史和近来几百年地医治和研究历讲的生动有力也不是易事。

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除了用科普的笔触去写人类对癌症认知的历史,作者还调查了“和癌症做斗争”的政治和社会运作。几乎是想象中科普作者的最佳语气。就像之前读过这本书的一位朋友说的,在我们这个时代大概每个人都会有机会旁观或亲历对抗癌症的战斗。

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除了用科普的笔触去写人类对癌症认知的历史,作者还调查了“和癌症做斗争”的政治和社会运作。几乎是想象中科普作者的最佳语气。就像之前读过这本书的一位朋友说的,在我们这个时代大概每个人都会有机会旁观或亲历对抗癌症的战斗。

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嗯,以后如果遇到别人求我推荐一本非虚构读物,不要太学术也不要太肤浅,大家都能读且都觉得好看的,就是这本了。不知道中译本翻得如何。

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