The Code Breaker

The Code Breaker pdf epub mobi txt 电子书 下载 2025

出版者:Simon & Schuster
作者:Walter Isaacson
出品人:
页数:560
译者:
出版时间:2021-3-9
价格:USD 29.99
装帧:Hardcover
isbn号码:9781982115852
丛书系列:
图书标签:
  • 密码学
  • 历史
  • 科学
  • 传记
  • 第二次世界大战
  • 计算机科学
  • 女性科学家
  • 情报
  • 克劳德·香农
  • 破解密码
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具体描述

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.

作者简介

Walter Isaacson, a professor of history at Tulane, has been CEO of the Aspen Institute, chair of CNN, and editor of Time. He is the author of Leonardo da Vinci; The Innovators; Steve Jobs; Einstein: His Life and Universe; Benjamin Franklin: An American Life; and Kissinger: A Biography, and the coauthor of The Wise Men: Six Friends and the World They Made. Visit him at Isaacson.Tulane.edu.

目录信息

读后感

评分

Informative, Entertaining, Thorougher, Balanced, and Up-to-date Some personal takeaways: 1. Scientic research, like venture investing or many other endeavors in life, rewards risk taking and audacity. You ought to aim high, pursue big dreams, and be willing...

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想找本一两年内的最新科普书来刷新一下自己,但没找到合适的。倒是看到这本传记口碑不错,觉得书里写的既然是生物科技前沿人物,那多多少少也该有些科普内容吧。 作为人物传记,这本书还是很不错的,没有按年代写流水账,即便是主角Doudna的经历,也是详略得当、重点突出,节奏...  

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1、 根据我目前的认知,大部分生命活动的调控是精细而复杂的,并非敲除或改变一段序列就能产生显著效果。生命系统的复杂性也预示任意改造一段序列可能会有意外后果。此外,脱靶效应也会限制基因编辑技术的人体应用。所以,大规模的基因设计短时期内还只是个愿景,但早早开始考...  

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这本书主要围绕Jennifer Doudna, 回顾了CRISPR和基因编辑的探讨. 写的跌宕起伏, 描述了科学研究者之间秘密竞争同时又对自然保护好奇心展开合作. 不同的研究者展示了非常不一样的个性. 后面几章讨论bioethics 和人类基因改造, 我不大喜欢. 作者自己个人想法太多,觉得有点肤浅, ...  

用户评价

评分

should be the code breakers. 一开始是抱着Bill Gates 推荐过所以想看,不得不说有点失望。但是看到Bill and Melinda Gates Foundation 资助了以后就也没那么意外了。

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作为对科技新闻有一定关注的读者,我是觉得传记大拿的这本新书略略有点水、有点散呀……可能书中纪事我多少有些了解,所以读来新鲜感不强。而厚厚近600页感觉有点四不像——既不是传记、也不是新闻调查;有点像在翻资料汇编,又有点像在刷公众号。 不过也不难看。最留下印象的几点: ➊用生物学词汇mosaic来形容人性的复杂多面向,a better description than grayscale; ➋第一次了解到biohackers(书中以Josiah Zayner为代表)这个群体。如何看待citizen science(民科)? ➌作者引用Michael Sandel教授关于“playing god”的论述; ➍D与C两位女科学家渐行渐远(不是闹翻)的友谊(研究合作与私交两个层面)。

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平平无奇 你好我好大家好

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很好的了解CRISP的科普

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感觉看了一部宫斗剧?

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