The Gene

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出版者:Scribner
作者:Siddhartha Mukherjee
出品人:
页数:608
译者:
出版时间:2016-5-17
价格:USD 32.00
装帧:Hardcover
isbn号码:9781476733500
丛书系列:
图书标签:
  • 科普
  • 基因
  • 生物
  • 医学
  • 英文原版
  • 生物学
  • 遗传学
  • biology
  • 基因
  • 遗传
  • 生物学
  • 科学
  • 进化
  • DNA
  • 遗传学
  • 生命
  • 科学史
  • 分子生物学
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具体描述

From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies—a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to “read” and “write” our own genetic information?

The extraordinary Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Throughout the narrative, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—cuts like a bright, red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome.

As The New Yorker said of The Emperor of All Maladies, “It’s hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion…An extraordinary achievement.” Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or “write” the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.

作者简介

Siddhartha Mukherjee is the author of The Emperor of All Maladies: A Biography of Cancer, winner of the 2011 Pulitzer Prize in general nonfiction, and The Laws of Medicine. He is the editor of Best Science Writing 2013Mukherjee is an assistant professor of medicine at Columbia University and a cancer physician and researcher. A Rhodes scholar, he graduated from Stanford University, University of Oxford, and Harvard Medical School. He has published articles in Nature, The New England Journal of Medicine, The New York Times, and Cell. He lives in New York with his wife and daughters.

目录信息

读后感

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最初拿到《基因传》,以为这只是一本科普读物,但当我读过之后,发现这本书的故事性也是蛮强的,而且书中的每个故事,都跟我们有关系。开始我甚至觉得这本500多页的“大块头儿”很难攻克,但是翻过几页之后,我感觉这本书就像推理小说一样,逻辑清晰、结构严谨。作者每每遇到问...  

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读完悉达多·穆克吉的《基因转》,被震撼到了。这本书比我读过的任何一本书都重要。 德尔斐神谕说“认识你自己”,其实我们每个人无时不刻在强化这一过程,有时通过新闻媒体,有时通过艺术作品,或者和有真知灼见的人对话,有意识或下意识地想解决我们是谁,从何而来,往何处...  

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读完悉达多·穆克吉的《基因转》,被震撼到了。这本书比我读过的任何一本书都重要。 德尔斐神谕说“认识你自己”,其实我们每个人无时不刻在强化这一过程,有时通过新闻媒体,有时通过艺术作品,或者和有真知灼见的人对话,有意识或下意识地想解决我们是谁,从何而来,往何处...  

用户评价

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条理清楚,简单明了,文笔也好。其中有几段关于基因学发展史以及基因与人类历史相互作用的文字真是怎么读都不厌。2018年的第一本书,非常值得。

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从门德尔植物园的豌豆到美国二十年代的优生学实践,从Paul Berg与学生们在Venus castle的饮酒对谈到遭遇失败的基因修改实践,Mukherjee的基因编年史用一种荡气回肠的方式自由的穿过自然科学研究与社会生活的隐形鸿沟。这在里,作为读者,我们看得见学者的坚韧,尊严,或者孤傲,也感受得到一门科学如何在各方力量的裹挟缠斗中寻求新的突破。

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出版社送了一本书,要写个短评。书很好,等不及翻译就看完了。《癌症传》的作者新著,厚的像词典,厚有厚的道理,可以说是最全的基因科普书了,从亚里士多德一路写到去年的研究成果,中间涵盖了几乎任何跟遗传学相关的重要内容。包括进化论、优生学、表观遗传,孟德尔的豌豆,摩尔的果蝇,人类基因草图,基因合成人胰岛素,变性,基因筛查和基因疗法。一路下来,你会看到西方一开始就从细处入手,哪怕在公元前,没有任何技术条件,亚里士多德们就在思索父母的特征是怎么传递给下一代的。虽然他们的假象极其幼稚,但就是这种直接的思维,带来可证伪的具体结论,进而实现不断进步。不像某医学,说什么心属火,肝属木,虚头八脑没法验证,说了几千年,还在原地踏步,还要死灰复燃,真是害人精。

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被作者这种博学又智慧的科学家深深迷倒!能把science写得优美严谨又有趣 读起来就不想停

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如果不写他自己家那点破事就更好了

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