From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies—a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to “read” and “write” our own genetic information?
The extraordinary Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
Throughout the narrative, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—cuts like a bright, red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome.
As The New Yorker said of The Emperor of All Maladies, “It’s hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion…An extraordinary achievement.” Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or “write” the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.
Siddhartha Mukherjee is the author of The Emperor of All Maladies: A Biography of Cancer, winner of the 2011 Pulitzer Prize in general nonfiction, and The Laws of Medicine. He is the editor of Best Science Writing 2013Mukherjee is an assistant professor of medicine at Columbia University and a cancer physician and researcher. A Rhodes scholar, he graduated from Stanford University, University of Oxford, and Harvard Medical School. He has published articles in Nature, The New England Journal of Medicine, The New York Times, and Cell. He lives in New York with his wife and daughters.
读完悉达多·穆克吉的《基因转》,被震撼到了。这本书比我读过的任何一本书都重要。 德尔斐神谕说“认识你自己”,其实我们每个人无时不刻在强化这一过程,有时通过新闻媒体,有时通过艺术作品,或者和有真知灼见的人对话,有意识或下意识地想解决我们是谁,从何而来,往何处...
评分《基因传》:一份普通人获取身体藏宝图的密码指南 读中信出版集团《基因传·众生之源》 文/方木鱼 我迄今仍然记得初读《史蒂夫·乔布斯传》的各种奇特体验,沉沉的夜里,辗转难眠,一灯如豆,轻翻书页,读到枯燥处时,那种“我浪费了这么宝贵的时间,这究竟是在干什么啊”的体...
评分mark一下,读到了希特勒的部分,残酷地快要读不下去了。第一次知道纳粹种族清洗竟然还有所谓的理论基础: Eugenics. 可笑,可叹,可耻,可悲! 自然科学因此蒙羞。一切的最开始是无辜的被诊断有先天性缺陷的孩子们被送进毒气办公室处死啊!我想知道这一切的疯狂如何平息,这一切...
评分mark一下,读到了希特勒的部分,残酷地快要读不下去了。第一次知道纳粹种族清洗竟然还有所谓的理论基础: Eugenics. 可笑,可叹,可耻,可悲! 自然科学因此蒙羞。一切的最开始是无辜的被诊断有先天性缺陷的孩子们被送进毒气办公室处死啊!我想知道这一切的疯狂如何平息,这一切...
评分人类从来没有像今天这样无限接近生命的真相,当我们能够掌控和改造人类基因时,“人类”的概念也许将从根本上发生改变,后人类时代正在来临。《基因传》所讲的故事,与每个人都息息相关。 到底是什么力量或机制才能解释人类个体截然不同的命运与选择呢?人们在18 世纪之前曾经...
出版社送了一本书,要写个短评。书很好,等不及翻译就看完了。《癌症传》的作者新著,厚的像词典,厚有厚的道理,可以说是最全的基因科普书了,从亚里士多德一路写到去年的研究成果,中间涵盖了几乎任何跟遗传学相关的重要内容。包括进化论、优生学、表观遗传,孟德尔的豌豆,摩尔的果蝇,人类基因草图,基因合成人胰岛素,变性,基因筛查和基因疗法。一路下来,你会看到西方一开始就从细处入手,哪怕在公元前,没有任何技术条件,亚里士多德们就在思索父母的特征是怎么传递给下一代的。虽然他们的假象极其幼稚,但就是这种直接的思维,带来可证伪的具体结论,进而实现不断进步。不像某医学,说什么心属火,肝属木,虚头八脑没法验证,说了几千年,还在原地踏步,还要死灰复燃,真是害人精。
评分Really eyes wide opening. We the humans as intelligent organisms who has learned to read and write our own instructions. Shelf: #textbook#????
评分条理清楚,简单明了,文笔也好。其中有几段关于基因学发展史以及基因与人类历史相互作用的文字真是怎么读都不厌。2018年的第一本书,非常值得。
评分如果不写他自己家那点破事就更好了
评分条理清楚,简单明了,文笔也好。其中有几段关于基因学发展史以及基因与人类历史相互作用的文字真是怎么读都不厌。2018年的第一本书,非常值得。
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