Molecular Neurosurgery with Targeted Toxins pdf epub mobi txt 電子書 下載2025
- 分子神經外科
- 靶嚮毒素
- 神經外科
- 分子生物學
- 藥物遞送
- 腫瘤治療
- 神經科學
- 精準醫療
- 創新療法
- 臨床研究
具體描述
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.
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