Mr. Tickle is the first book in the Mr. Men series by Roger Hargreaves.

The character of Mr. Tickle was created when Roger's 8-year-old son, Adam, asked, "What does a tickle look like?" Like all Mr. Men, Mr. Tickle has a simplistic look. He is orange with long arms and a small blue hat.

In 2001, for the 30th anniversary of the Mr. Men, Mr. Tickle's book was released as a collector's edition hardback. It included a foreword from Adam Hargreaves.

Mr. Tickle's story begins with him in bed and making himself breakfast without getting up because of his "extraordinarily long arms". He then decides that it is a tickling sort of day and so goes around town tickling people - a teacher, a policeman, a greengrocer, a station guard, a doctor, a butcher and a postman. The book ends with a warning that Mr. Tickle could be lurking around your doorway, waiting to tickle you.

Mr. Tickle appears under the titles Monsieur Chatouille (French), Don Cosquillas (Spanish), Mr. Goglais (Welsh), Unser Herr Killekille (German), Meneertje Kietel (Dutch), Ο Κύριος Γαργαλίτσας (Greek), 搔癢先生 (Taiwan), 간지럼씨 (Korean), Fætter Kilderik (Danish), Gubben Killekill (Swedish), מר דגדוג (Hebrew), Mr. Csiki (Hungarian)

In the 2008 TV series The Mr. Men Show, Mr. Tickle remains relatively the same in looks, though his arms are normally sized, but can stretch out when needed. However, he tickles other Mr. Men and Little Misses (due to the obvious absence of humans in Dillydale.) As far as character traits goes, he is still determined to tickle everyone he interacts with, but instead of doing it for mischief he does it to make people happy and will stop when nobody wants him to tickle them, save for when the opportunity knocks with Mr. Grumpy, who appears to be his favorite target. He also gets his own catchphrase "I think somebody needs a tickle!" (In "Amusement Park", he says, "I know a grumpy grape who needs a tickle!") In the US and UK Versions, he is voiced by Jeff Stewart and Rob Rackstraw.

Mr. Tickle also featured in some of the other books, such as Little Miss Magic. In her story, she reduces his arms to normal length so he can no longer be annoying and tickle anyone. She eventually gives him his arms back when he begs for forgiveness and promises to reduce his actions to one tickle a day. However, he gets his revenge as soon as he is out of the room with his long arms and uses his one tickle for the day on her.