具體描述
《生物化學》是雙語教材，總結多年教學中沉澱的經驗，按照醫學各專業的特點，將生物化學劃分為生物大分子的結構與功能、物質代謝、基因錶達和專題篇4個部分，努力構建係統化課程，從學生興趣、認知規律和探究方便齣發閤理設計教材的結構，注意聯係實際，適度擴大學生的知識麵和應用能力，突齣教材中知識結構的科學化。並以鮮活靈動的色彩、圖文並茂的版麵、熟悉的例子吸引剛入門的醫學生，讓學生感受課程學習的趣味性和挑戰性，將是一係統性強、可讀性強、深受學生喜愛的教材。
著者簡介
圖書目錄
PART Ⅰ : STRUCTURE AND FUNCTION OF BIOMACROMOLECULE
Chapter 1 Structure and Function of Protein
SECTION 1 THE COMPOSITION OF PROTEIN
1.1 Amino acid
1.2 Peptide
1.3 Some small polypeptides have biological activity
SECTION 2 MOLECULAR STRUCTURE OF PROTEINS
2.1 Primary structure
2.2 Secondary structure
2.3 Tertiary structure
2.4 Major noncovalent bond
2.5 Quaternary structure
SECTION 3 RELATION BETWEEN STRUCTURE AND FUNCTION OF PROTEINS
3.1 Primary structure and potential function of protein
3.2 Spatial structure shows the function of protein
SECTION 4 CHEMICAL AND PHYSICAL PROPERTIES OF PROTEINS
4.1 Ultraviolet absorption spectrum of protein
4.2 Isoelectric point (pI)
4.3 Denaturation of protein
SECTION 5 ISOLATION, PURIFICATION AND SEQUENCING OF PROTEINS
5.1 Dialysis and ultrafiltration
5.2 Precipitation with acetone, salting precipitation and immunoprecipitation
5.3 Chromatographic separations
5.4 Electrophoresis
5.5 Ultracentrifugation
SUMMARY
Chapter 2 Chemistry of Nucleic Acids
SECTION 1 MOLECULAR COMPOSITION OF NUCLEIC ACIDS
1.1 Basic components
1.2 Nucleosides
1.3 Mononucleotides
SECTION 2 MOLECULAR STRUCTURES OF DNA
2.1 Primary structure of nucleic acid
2.2 Chargaff's rules
2.3 Secondary structure of DNA
SECTION 3 PHYSICO-CHEMICAL PROPERTIES OF NUCLEIC ACIDS
3.1 Viscosity
3.2 Ultraviolet absorption
3.3 Denaturation and renaturation of DNA
3.4 Hydrolysis of acid or alkali
SECTION 4 STRUCTURES OF RNA
4.1 Messenger RNA
4.2 Transfer RNA
4.3 Ribosomal RNA
SUMMARY
Chapter 3 Enzymes
SECTION 1 THE MOLECULAR COMPOSITION AND FUNCTION OF ENZYMES
1.1 The molecular composition of enzymes
1.2 The active center of enzymes
1.3 Many enzymes require cofactors
SECTION 2 PROPERTIES AND MECHANISM OF ENZYME CATALYSIS
2.1 Remarkable properties of enzymes
2.2 Mechanism of enzyme catalysis
SECTION 3 THE KINETICS OF ENZYME CATALYSIS
3.1 Catalysis occurs at the active site
3.2 Multiple factors affect the rates of enzyme-catalyzed reactions
3.3 Initial rate is proportionate to enzyme concentration
3.4 Substrate concentration affects reaction rate
3.5 The Michaelis-Menten equations model the effects of substrate concentration
3.6 Kinetic analysis distinguishes competitive from noncompetitive inhibition
SECTION 4 ZYMOGENS AND ISOZYMES
4.1 Zymogens and zymogen activation
4.2 Isozymes are physically distinct forms of the same catalytic activity
……
PART Ⅱ : METABOLISM
PART Ⅲ : GENE EXPRESSING
PART Ⅳ : SPECIAL TOPICS
· · · · · · (收起)
Chapter 1 Structure and Function of Protein
SECTION 1 THE COMPOSITION OF PROTEIN
1.1 Amino acid
1.2 Peptide
1.3 Some small polypeptides have biological activity
SECTION 2 MOLECULAR STRUCTURE OF PROTEINS
2.1 Primary structure
2.2 Secondary structure
2.3 Tertiary structure
2.4 Major noncovalent bond
2.5 Quaternary structure
SECTION 3 RELATION BETWEEN STRUCTURE AND FUNCTION OF PROTEINS
3.1 Primary structure and potential function of protein
3.2 Spatial structure shows the function of protein
SECTION 4 CHEMICAL AND PHYSICAL PROPERTIES OF PROTEINS
4.1 Ultraviolet absorption spectrum of protein
4.2 Isoelectric point (pI)
4.3 Denaturation of protein
SECTION 5 ISOLATION, PURIFICATION AND SEQUENCING OF PROTEINS
5.1 Dialysis and ultrafiltration
5.2 Precipitation with acetone, salting precipitation and immunoprecipitation
5.3 Chromatographic separations
5.4 Electrophoresis
5.5 Ultracentrifugation
SUMMARY
Chapter 2 Chemistry of Nucleic Acids
SECTION 1 MOLECULAR COMPOSITION OF NUCLEIC ACIDS
1.1 Basic components
1.2 Nucleosides
1.3 Mononucleotides
SECTION 2 MOLECULAR STRUCTURES OF DNA
2.1 Primary structure of nucleic acid
2.2 Chargaff's rules
2.3 Secondary structure of DNA
SECTION 3 PHYSICO-CHEMICAL PROPERTIES OF NUCLEIC ACIDS
3.1 Viscosity
3.2 Ultraviolet absorption
3.3 Denaturation and renaturation of DNA
3.4 Hydrolysis of acid or alkali
SECTION 4 STRUCTURES OF RNA
4.1 Messenger RNA
4.2 Transfer RNA
4.3 Ribosomal RNA
SUMMARY
Chapter 3 Enzymes
SECTION 1 THE MOLECULAR COMPOSITION AND FUNCTION OF ENZYMES
1.1 The molecular composition of enzymes
1.2 The active center of enzymes
1.3 Many enzymes require cofactors
SECTION 2 PROPERTIES AND MECHANISM OF ENZYME CATALYSIS
2.1 Remarkable properties of enzymes
2.2 Mechanism of enzyme catalysis
SECTION 3 THE KINETICS OF ENZYME CATALYSIS
3.1 Catalysis occurs at the active site
3.2 Multiple factors affect the rates of enzyme-catalyzed reactions
3.3 Initial rate is proportionate to enzyme concentration
3.4 Substrate concentration affects reaction rate
3.5 The Michaelis-Menten equations model the effects of substrate concentration
3.6 Kinetic analysis distinguishes competitive from noncompetitive inhibition
SECTION 4 ZYMOGENS AND ISOZYMES
4.1 Zymogens and zymogen activation
4.2 Isozymes are physically distinct forms of the same catalytic activity
……
PART Ⅱ : METABOLISM
PART Ⅲ : GENE EXPRESSING
PART Ⅳ : SPECIAL TOPICS
· · · · · · (收起)
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