The hERG Cardiac Potassium Channel pdf epub mobi txt 电子书下载 2024

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Novartis Foundation

John Wiley & Sons Inc

2005-4

297

1310.80元

HRD

9780470021408

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发表于2024-11-10

The hERG Cardiac Potassium Channel epub 下载 mobi 下载 pdf 下载 txt 电子书下载 2024

The hERG Cardiac Potassium Channel pdf epub mobi txt 电子书下载 2024

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This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks. Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.

The hERG Cardiac Potassium Channel 下载 mobi epub pdf txt 电子书