具体描述
A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008).
The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers.
This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology.
* The most comprehensive source of up-to-date data on the neurobiology of aging, review articles cover: normal, sensory and cognitive aging; neuroendocrine, structural and molecular factors; and fully address both patholgy and intervention
* Chapters represent an authoritative selection of relevant material from the most comprehensive source of information about neuroscience ever assembled, (Encyclopedia of Neuroscience), synthesizing information otherwise
dispersed across a number of journal articles and book chapters, and saving researchers the time consuming process of finding and integrating this information themselves
* Offering outstanding scholarship, each chapter is written by an expert in the topic area and over 20% of chapters feature international contributors, (representing 11 countries)
* Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
* Fully explores various pathologies associated with the aging brain (Alzheimer's, dementia, Parkinson's, memory disorders, stroke, Down's syndrome, etc.)
* Coverage of disorders and key interventions makes the volume relevant to clinicians as well as researchers
* Heavily illustrated with over 100 color figures
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毫无疑问，《Handbook of the Neuroscience of Aging》是一部极具分量的学术巨著，它为我提供了一个俯瞰衰老神经科学全景的绝佳视角。书中深入剖析了衰老过程中大脑发生的各种分子、细胞和系统层面的改变，从神经递质的失衡到突触的可塑性减弱，再到神经元网络的重塑，都进行了详尽而严谨的阐释。我尤其欣赏其对当前研究空白和未来发展方向的清晰界定，这对于我这样的研究者来说，无疑是宝贵的指引。书中对多种疾病模型的研究方法和结果的介绍，也让我对如何设计和评估干预策略有了更深刻的理解。它并没有简单地罗列事实，而是通过逻辑严密的论述，构建起一个完整的知识体系，让我能够系统地掌握衰老神经科学的最新动态。这本书的参考文献列表之丰富，足以说明其内容的深度和广度，它绝对是任何想要深入了解此领域专业人士的必备参考书。
评分这本《Handbook of the Neuroscience of Aging》真是一把开启了大脑深层奥秘的钥匙，它以一种近乎诗意的方式，将我们带入了一个关于时间和记忆、学习与遗忘的奇妙旅程。读这本书的过程，就像是在探索一座宏伟的知识宫殿，每一个章节都像是一个精心设计的房间，里面陈列着关于大脑衰老最前沿的发现。我特别着迷于关于“认知储备”的讨论，作者用一系列形象的比喻，将这个抽象的概念变得触手可及，让我明白了积极的生活方式和持续的学习如何能够为大脑构建一道坚实的“防火墙”，抵御衰老的侵蚀。书中对于不同年龄段大脑结构和功能的细致描绘，也让我对自身的变化有了更清晰的认知，不再盲目地恐惧衰老，而是学会了以一种更加积极和科学的态度去面对。整本书的逻辑清晰，论证严谨，虽然涉及了大量的高等知识，但作者的表达方式却异常地亲切，仿佛一位经验丰富的向导，引领我在知识的海洋中遨游，让我一次又一次地发出“原来如此”的感叹。
评分《Handbook of the Neuroscience of Aging》是一次令人振奋的思想启迪之旅。它如同一位博学的导师，用一种充满智慧和洞察力的方式，向我揭示了衰老背后那些错综复杂的神经科学机制。我被书中关于“脑健康”的积极干预策略所深深吸引，作者们并非仅仅描绘衰老的负面影响，而是着重探讨了如何通过生活方式的调整、认知训练以及社会参与，来优化大脑功能，延缓甚至逆转部分衰老带来的变化。书中关于睡眠、运动、饮食对大脑健康影响的科学分析，让我开始重新审视自己的日常生活习惯，并意识到这些看似微不足道的改变，对大脑的长期健康有着多么重要的意义。这本书不仅仅是一份科学报告，更是一份关于如何积极拥抱生命、提升生活品质的行动指南，它让我对未来的生活充满了信心和希望。
评分这是一本让我重塑对“衰老”认知的奇书。在阅读《Handbook of the Neuroscience of Aging》之前，我总觉得衰老就是一种不可逆的生理退化，但这本书彻底颠覆了我的看法。它让我了解到，大脑的衰老并非全然是衰败，而是一个复杂且动态的过程，其中充满了适应和代偿的机制。作者以详实的案例和科学的证据，揭示了许多看似衰退的认知能力，实际上可能是一种更加高效的、适应老年生活的新型认知模式。书中关于“智慧”的神经科学解释尤其令我着迷，它不再将智慧视为年轻人的专利，而是将其与经验、情感和社会联系紧密结合，展现了老年人独特的认知优势。这本书让我看到了衰老的光辉一面，让我对未来的人生充满了期待，不再畏惧岁月的流逝，而是渴望拥抱它带来的智慧和沉淀。
评分这本书简直是一次知识的奇幻漂流，让我从一个对衰老神经科学仅有模糊概念的门外汉，逐渐触摸到了这个领域最前沿的脉搏。初拿到手时，厚重的体量和密集的专业术语让我有些畏惧，但翻开第一页，我就被作者深入浅出的讲解所吸引。他们并没有一股脑地堆砌枯燥的数据和晦涩的理论，而是巧妙地将复杂的概念剥茧抽丝，用生动的比喻和贴近生活的例子来解释。我尤其欣赏其中关于“可塑性”章节的阐述，它颠覆了我过去对大脑“不可逆转”衰退的刻板印象，让我看到了在衰老过程中，大脑依然存在的学习和适应能力。书中对各种神经退行性疾病的最新研究进展也进行了详尽的梳理，从基因层面的探索到靶向治疗的突破，都让我惊叹于人类在对抗衰老和疾病方面的努力。读完这本书，我感觉自己对如何健康地老去，以及如何更好地理解和支持那些经历衰老的人群，都有了更深刻的认识，这不仅仅是一本学术著作，更是一份关于生命、智慧和希望的启迪。
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