Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.
具體描述
讀後感
It has been a long time since I devoted myself to learning something. I wanted to learn R around 2007, and consulted to friends in CBI. At then, I was using R to analyze my data while I began to learn this new language. Difficulties arised, and I stopped....
評分It has been a long time since I devoted myself to learning something. I wanted to learn R around 2007, and consulted to friends in CBI. At then, I was using R to analyze my data while I began to learn this new language. Difficulties arised, and I stopped....
評分It has been a long time since I devoted myself to learning something. I wanted to learn R around 2007, and consulted to friends in CBI. At then, I was using R to analyze my data while I began to learn this new language. Difficulties arised, and I stopped....
評分It has been a long time since I devoted myself to learning something. I wanted to learn R around 2007, and consulted to friends in CBI. At then, I was using R to analyze my data while I began to learn this new language. Difficulties arised, and I stopped....
評分It has been a long time since I devoted myself to learning something. I wanted to learn R around 2007, and consulted to friends in CBI. At then, I was using R to analyze my data while I began to learn this new language. Difficulties arised, and I stopped....
用戶評價
Wolfgang先生推薦的這本書用來分析affymetrix真的又入門又實用
评分Case study, on microarray
评分Case study, on microarray
评分Wolfgang先生推薦的這本書用來分析affymetrix真的又入門又實用
评分以前這些書都隻有電子版可以看，在圖書館無意中看到，就藉迴來，這麼多年用bioconductor，書中的topic都是有接觸到的，做為一本case study的書，也隻是show一些代碼，流程化的東西。其實也沒啥好看的，都是需要什麼，現學現賣，這本書隻是從頭到尾隨便翻過去。
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