Drug-like Properties pdf epub mobi txt 电子书 下载 2024


Drug-like Properties

简体网页||繁体网页
Edward Kerns
Academic Press
2008-02-01
552
USD 99.95
Hardcover
9780123695208

图书标签: 药物研发  制药业  医药   


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发表于2024-12-24

Drug-like Properties epub 下载 mobi 下载 pdf 下载 txt 电子书 下载 2024

Drug-like Properties epub 下载 mobi 下载 pdf 下载 txt 电子书 下载 2024

Drug-like Properties pdf epub mobi txt 电子书 下载 2024



图书描述

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.

The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties.

* Serves as an essential working handbook aimed at scientists and students in medicinal chemistry

* Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies

* Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Drug-like Properties 下载 mobi epub pdf txt 电子书

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Drug-like Properties pdf epub mobi txt 电子书 下载
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I have to admit that this is the most wonderful book focusing on drug-like properties. It is especially valuable for any beginner to start the pharmaceutic exploration. Really excellent.

评分

I have to admit that this is the most wonderful book focusing on drug-like properties. It is especially valuable for any beginner to start the pharmaceutic exploration. Really excellent.

评分

I have to admit that this is the most wonderful book focusing on drug-like properties. It is especially valuable for any beginner to start the pharmaceutic exploration. Really excellent.

评分

I have to admit that this is the most wonderful book focusing on drug-like properties. It is especially valuable for any beginner to start the pharmaceutic exploration. Really excellent.

评分

I have to admit that this is the most wonderful book focusing on drug-like properties. It is especially valuable for any beginner to start the pharmaceutic exploration. Really excellent.

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Drug-like Properties pdf epub mobi txt 电子书 下载 2024


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