Pharmacophores and Pharmacophore Searches pdf epub mobi txt 电子书下载 2024

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Hoffmann, Remy D. 编

Wiley-VCH

2006-10-30

375

USD 225.00

Hardcover

9783527312504

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发表于2024-11-13

Pharmacophores and Pharmacophore Searches epub 下载 mobi 下载 pdf 下载 txt 电子书下载 2024

Pharmacophores and Pharmacophore Searches pdf epub mobi txt 电子书下载 2024

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This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties. With its critical evaluation of pharmacophore-based strategies, this book represents a valuable aid for project leaders and decision-makers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.

Pharmacophores and Pharmacophore Searches 下载 mobi epub pdf txt 电子书