Molecular Chaperones and Cell Signalling pdf epub mobi txt 電子書 下載2025
- 分子伴侶蛋白
- 細胞信號傳導
- 蛋白質摺疊
- 蛋白質穩態
- 應激反應
- 細胞生物學
- 生物化學
- 信號通路
- 疾病機製
- 分子生物學
具體描述
Originally published in 2005, this book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones?
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